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Speckle-type POZ protein, SPOP, is involved in the DNA damage response
Speckle-type POZ protein (SPOP) is an adaptor of the cullin 3-based ubiquitin ligase responsible for the degradation of oncoproteins frequently overexpressed in many tumor cells. Altered expression and somatic mutations of SPOP have been observed in various tumor types with chromosomal aberrations,...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4123640/ https://ncbi.nlm.nih.gov/pubmed/24451148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu022 |
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