The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy

The mitochondria-targeted antioxidant SkQ1 is a novel drug thought to retard development of age-related diseases. It has been shown that SkQ1 reduces clinical signs of retinopathy in senescence-accelerated OXYS rats, which are a known animal model of human age-related macular degeneration (AMD). The...

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Bibliographic Details
Main Authors: Perepechaeva, M. L., Grishanova, A. Yu., Rudnitskaya, E. A., Kolosova, N. G.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123489/
https://ncbi.nlm.nih.gov/pubmed/25132985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/530943
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