Mitochondrial Translocation of p53 Modulates Neuronal Fate by Preventing Differentiation-Induced Mitochondrial Stress

Aims: Apoptosis regulatory proteins, such as p53, play a pivotal role in neural differentiation, through mechanisms independent of cell death. In addition, p53 has been identified as an important regulator of mitochondrial survival response, maintaining mitochondrial DNA (mtDNA) integrity and oxidat...

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Bibliografiske detaljer
Main Authors: Xavier, Joana M., Morgado, Ana L., Solá, Susana, Rodrigues, Cecília M.P.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2014
Fag:
Original Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123470/
https://ncbi.nlm.nih.gov/pubmed/24329038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5417
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