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Mitochondrial Translocation of p53 Modulates Neuronal Fate by Preventing Differentiation-Induced Mitochondrial Stress

Aims: Apoptosis regulatory proteins, such as p53, play a pivotal role in neural differentiation, through mechanisms independent of cell death. In addition, p53 has been identified as an important regulator of mitochondrial survival response, maintaining mitochondrial DNA (mtDNA) integrity and oxidat...

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Detalhes bibliográficos
Main Authors: Xavier, Joana M., Morgado, Ana L., Solá, Susana, Rodrigues, Cecília M.P.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123470/
https://ncbi.nlm.nih.gov/pubmed/24329038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5417
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