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Thermal Enhancement with Optically Activated Gold Nanoshells Sensitizes Breast Cancer Stem Cells to Radiation Therapy

Breast cancer metastasis and disease recurrence are hypothesized to result from residual cancer stem cells, also referred to as tumor-initiating cells, which evade initial treatment. Using both syngeneic mouse and human xenograft models of triple-negative breast cancer, we have demonstrated that a s...

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Autors principals: Atkinson, Rachel L., Zhang, Mei, Diagaradjane, Parmeswaran, Peddibhotla, Sirisha, Contreras, Alejandro, Hilsenbeck, Susan G., Woodward, Wendy A., Krishnan, Sunil, Chang, Jenny C., Rosen, Jeffrey M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123313/
https://ncbi.nlm.nih.gov/pubmed/20980696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3001447
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