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Mechanism and implications of CXCR4-mediated integrin activation by Porphyromonas gingivalis
In monocytes and macrophages, the interaction of Porphyromonas gingivalis with Toll-like receptor 2 (TLR2) leads to the activation of a MyD88-dependent antimicrobial pathway and a phosphatidylinositol-3 kinase (PI3K)-dependent proadhesive pathway, which activates the β(2) integrin complement recepto...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4123224/ https://ncbi.nlm.nih.gov/pubmed/23331495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/omi.12021 |
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