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Mechanism and implications of CXCR4-mediated integrin activation by Porphyromonas gingivalis

In monocytes and macrophages, the interaction of Porphyromonas gingivalis with Toll-like receptor 2 (TLR2) leads to the activation of a MyD88-dependent antimicrobial pathway and a phosphatidylinositol-3 kinase (PI3K)-dependent proadhesive pathway, which activates the β(2) integrin complement recepto...

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Detalhes bibliográficos
Main Authors: Hajishengallis, George, McIntosh, Megan L., Nishiyama, So-ichiro, Yoshimura, Fuminobu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123224/
https://ncbi.nlm.nih.gov/pubmed/23331495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/omi.12021
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