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Fluvoxamine alleviates ER stress via induction of Sigma-1 receptor
We recently demonstrated that endoplasmic reticulum (ER) stress induces sigma-1 receptor (Sig-1R) expression through the PERK pathway, which is one of the cell's responses to ER stress. In addition, it has been demonstrated that induction of Sig-1R can repress cell death signaling. Fluvoxamine...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4123092/ https://ncbi.nlm.nih.gov/pubmed/25032855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.301 |
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