Fluvoxamine alleviates ER stress via induction of Sigma-1 receptor

We recently demonstrated that endoplasmic reticulum (ER) stress induces sigma-1 receptor (Sig-1R) expression through the PERK pathway, which is one of the cell's responses to ER stress. In addition, it has been demonstrated that induction of Sig-1R can repress cell death signaling. Fluvoxamine...

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Detalhes bibliográficos
Main Authors: Omi, T, Tanimukai, H, Kanayama, D, Sakagami, Y, Tagami, S, Okochi, M, Morihara, T, Sato, M, Yanagida, K, Kitasyoji, A, Hara, H, Imaizumi, K, Maurice, T, Chevallier, N, Marchal, S, Takeda, M, Kudo, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123092/
https://ncbi.nlm.nih.gov/pubmed/25032855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.301
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