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Rer1p regulates the ER retention of immature rhodopsin and modulates its intracellular trafficking
Rhodopsin is a pigment in photoreceptor cells. Some rhodopsin mutations cause the protein to accumulate in the endoplasmic reticulum (ER), leading to photoreceptor degeneration. Although several mutations have been reported, how mutant rhodopsin is retained in the ER remains unclear. In this study,...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4122963/ https://ncbi.nlm.nih.gov/pubmed/25096327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05973 |
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