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Rer1p regulates the ER retention of immature rhodopsin and modulates its intracellular trafficking

Rhodopsin is a pigment in photoreceptor cells. Some rhodopsin mutations cause the protein to accumulate in the endoplasmic reticulum (ER), leading to photoreceptor degeneration. Although several mutations have been reported, how mutant rhodopsin is retained in the ER remains unclear. In this study,...

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Autors principals: Yamasaki, Akinori, Hara, Taichi, Maejima, Ikuko, Sato, Miyuki, Sato, Katsuya, Sato, Ken
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122963/
https://ncbi.nlm.nih.gov/pubmed/25096327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05973
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