Nonmigraine-associated TRESK K(+) channel variant C110R does not increase the excitability of trigeminal ganglion neurons

Recent genetic studies suggest that dysfunction of ion channels and transporters may contribute to migraine pathophysiology. A migraine-associated frameshift mutation in the TWIK-related spinal cord K(+) (TRESK) channel results in nonfunctional channels. Moreover, mutant TRESK subunits exert a domin...

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Hlavní autoři: Guo, Zhaohua, Liu, Ping, Ren, Fei, Cao, Yu-Qing
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
Témata:
Cellular and Molecular Properties of Neurons
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122697/
https://ncbi.nlm.nih.gov/pubmed/24805079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00267.2014
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