Cyclosporine A in Atopic Dermatitis Modulates activated inflammatory pathways and reverses epidermal pathology

BACKGROUND: Atopic dermatitis (AD) is the most common inflammatory disease. Evolving disease models link changes in epidermal growth and differentiation to Th2/Th22 cytokine activation. However, these models have not been tested by in-vivo suppression of T-cell cytokines. CsA is an immune-suppressan...

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Main Authors: Khattri, Saakshi, Shemer, Avner, Rozenblit, Mariya, Suárez-Fariñas, Mayte, Dhingra, Nikhil, Czarnowicki, Tali, Finney, Robert, Gilleaudeau, Patricia, Sullivan-Whalen, Mary, Zheng, Xiuzhong, Xu, Hui, Cardinale, Irma, de Guzman Strong, Cristina, Gonzalez, Juana, Krueger, Jim G, Guttman-Yassky, Emma
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122665/
https://ncbi.nlm.nih.gov/pubmed/24786238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.03.003
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