Gene expression of peripheral blood cells reveals pathways downstream of glucocorticoid receptor antagonism and nab-paclitaxel treatment

OBJECTIVES: While paclitaxel treatment is associated with leukopenia, the mechanisms that underlie this effect are not well-characterized. Additionally, despite the importance of glucocorticoid signaling in cancer treatment, the genomic effects of glucocorticoid receptor (GR) antagonism by mifeprist...

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Библиографические подробности
Главные авторы: Maranville, Joseph C, Nanda, Rita, Fleming, Gini F, Skor, Maxwell N, Di Rienzo, Anna, Conzen, Suzanne D
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122588/
https://ncbi.nlm.nih.gov/pubmed/25000515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000077
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