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Self-assembled nanoparticles based on the c(RGDfk) peptide for the delivery of siRNA targeting the VEGFR2 gene for tumor therapy

The clinical application of small interfering RNA (siRNA) has been restricted by their poor intracellular uptake, low serum stability, and inability to target specific cells. During the last several decades, a great deal of effort has been devoted to exploring materials for siRNA delivery. In this s...

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Autores principales: Liu, Li, Liu, Xiaoxia, Xu, Qian, Wu, Ping, Zuo, Xialin, Zhang, Jingjing, Deng, Houliang, Wu, Zhuomin, Ji, Aimin
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122582/
https://ncbi.nlm.nih.gov/pubmed/25114522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S63717
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