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Inhibition of DNA Methylation Alters Chromatin Organization, Nuclear Positioning and Activity of 45S rDNA Loci in Cycling Cells of Q. robur

Around 2200 copies of genes encoding ribosomal RNA (rRNA) in pedunculate oak, Quercus robur, are organized into two rDNA loci, the major (NOR-1) and the minor (NOR-2) locus. We present the first cytogenetic evidence indicating that the NOR-1 represents the active nucleolar organizer responsible for...

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Autors principals: Bočkor, Vedrana Vičić, Barišić, Darko, Horvat, Tomislav, Maglica, Željka, Vojta, Aleksandar, Zoldoš, Vlatka
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122370/
https://ncbi.nlm.nih.gov/pubmed/25093501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103954
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