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Defining Features of Protective CD4 T cell responses to Mycobacterium tuberculosis

CD4 T cells are critical for control of Mycobacterium tuberculosis (Mtb) infection and represent the best hope for vaccine-elicited protection. However, little is understood about the properties of Mtb-specific CD4 T cells that mediate control, and the lack of correlates of protection present a sign...

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Bibliographic Details
Main Authors: Sakai, Shunsuke, Mayer-Barber, Katrin D., Barber, Daniel L.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122329/
https://ncbi.nlm.nih.gov/pubmed/25000593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2014.06.003
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