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Link between DNA damage and centriole disengagement/reduplication in untransformed human cells ()

The radiation and radiomimetic drugs used to treat human tumors damage DNA in both cancer cells and normal proliferating cells. Centrosome amplification after DNA damage is well established for transformed cell types but is sparsely reported and not fully understood in untransformed cells. We charac...

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Hlavní autoři: Douthwright, Stephen, Sluder, Greenfield
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122266/
https://ncbi.nlm.nih.gov/pubmed/24532022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24579
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