Efficient derivation of cortical glutamatergic neurons from human pluripotent stem cells: A model system to study neurotoxicity in Alzheimer's disease

Alzheimer's disease (AD) is among the most prevalent forms of dementia affecting the aging population, and pharmacological therapies to date have not been successful in preventing disease progression. Future therapeutic efforts may benefit from the development of models that enable basic invest...

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Main Authors: Vazin, Tandis, Ball, K. Aurelia, Lu, Hui, Park, Hyungju, Ataeijannati, Yasaman, Head-Gordon, Teresa, Poo, Mu-ming, Schaffer, David V.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122237/
https://ncbi.nlm.nih.gov/pubmed/24055772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.09.005
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