Haptoglobin increases with age in rat hippocampus and modulates Apolipoprotein E mediated cholesterol trafficking in neuroblastoma cell lines

Alteration in cholesterol metabolism has been implicated in the pathogenesis of several neurodegenerative disorders. Apolipoprotein E (ApoE) is the major component of brain lipoproteins supporting cholesterol transport. We previously reported that the acute-phase protein Haptoglobin (Hpt) binds ApoE...

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Detalhes bibliográficos
Main Authors: Spagnuolo, Maria Stefania, Maresca, Bernardetta, Mollica, Maria Pina, Cavaliere, Gina, Cefaliello, Carolina, Trinchese, Giovanna, Esposito, Maria Grazia, Scudiero, Rosaria, Crispino, Marianna, Abrescia, Paolo, Cigliano, Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122225/
https://ncbi.nlm.nih.gov/pubmed/25140128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00212
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