Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease

Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder associated with allergic hypersensitivity to food. We interrogated >1.5 million genetic variants in European EoE cases and subsequently in a multi-site cohort with local and out-of-study control subjects. In addition to replication...

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Autors principals: Kottyan, Leah C., Davis, Benjamin P., Sherrill, Joseph D., Liu, Kan, Rochman, Mark, Kaufman, Kenneth, Weirauch, Matthew T., Vaughn, Samuel, Lazaro, Sara, Rupert, Andrew M., Kohram, Mojtaba, Stucke, Emily M., Kemme, Katherine A., Magnusen, Albert, He, Hua, Dexheimer, Phillip, Chehade, Mirna, Wood, Robert A., Pesek, Robbie D., Vickery, Brian P., Fleischer, David M., Lindbad, Robert, Sampson, Hugh A., Mukkada, Vince, Putnam, Phil E., Abonia, J. Pablo, Martin, Lisa J., Harley, John B., Rothenberg, Marc E.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121957/
https://ncbi.nlm.nih.gov/pubmed/25017104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3033
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