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ADAMTS13 exerts a thrombolytic effect in microcirculation
Recombinant tissue plasminogen activator (r-tPA) is the drug of choice for thrombolysis, but it is associated with a significant risk of bleeding and is not always successful. By cleaving von Willebrand factor (VWF), the metalloprotease ADAMTS13 (a disintegrin-like and metalloprotease with thrombosp...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121884/ https://ncbi.nlm.nih.gov/pubmed/22782575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH12-01-0046 |
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