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Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness to stress
The extensive links between proteotoxic stress, protein aggregation and pathologies ranging from aging to neurodegeneration underscore the importance of understanding how cells manage protein misfolding. Using live-cell imaging, we here determine the fate of stress-induced misfolded proteins from th...
שמור ב:
Main Authors: | , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
2013
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121856/ https://ncbi.nlm.nih.gov/pubmed/24036477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2838 |
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