Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1β production in acute glaucoma

Acute glaucoma is a sight-threatening condition characterized by a sudden and substantial rise in intraocular pressure (IOP) and consequent retinal ganglion cell (RGC) death. Angle closure glaucoma, a common cause of glaucoma in Asia that affects tens of millions of people worldwide, often presents...

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Bibliographic Details
Main Authors: Chi, Wei, Li, Fei, Chen, Hongrui, Wang, Yandong, Zhu, Yingting, Yang, Xuejiao, Zhu, Jie, Wu, Frances, Ouyang, Hong, Ge, Jian, Weinreb, Robert N., Zhang, Kang, Zhuo, Yehong
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121847/
https://ncbi.nlm.nih.gov/pubmed/25024200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402819111
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