Opposing roles of Prostaglandin D(2) receptors in ulcerative colitis

Pro-resolution functions were reported for Prostaglandin D(2) (PGD(2)) in colitis, but the role of its two receptors, DP and in particular CRTH2 are less well defined. We investigated DP and CRTH2 expression and function during human and murine ulcerative colitis (UC). Expression of receptors was me...

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Main Authors: Sturm, Eva M., Radnai, Balazs, Jandl, Katharina, Stančić, Angela, Parzmair, Gerald P., Högenauer, Christoph, Kump, Patrizia, Wenzl, Heimo, Petritsch, Wolfgang, Pieber, Thomas R., Schuligoi, Rufina, Marsche, Gunther, Ferreirós, Nerea, Heinemann, Akos, Schicho, Rudolf
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121674/
https://ncbi.nlm.nih.gov/pubmed/24929001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303484
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