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Interleukin-1β mediates macrophage-induced impairment of insulin signaling in human primary adipocytes
Adipose tissue expansion during obesity is associated with increased macrophage infiltration. Macrophage-derived factors significantly alter adipocyte function, inducing inflammatory responses and decreasing insulin sensitivity. Identification of the major factors that mediate detrimental effects of...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121578/ https://ncbi.nlm.nih.gov/pubmed/24918199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00430.2013 |
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