Platelet Activating Factor Receptor Activation Improves siRNA Uptake and RNAi Responses in Well-differentiated Airway Epithelia

Well-differentiated human airway epithelia present formidable barriers to efficient siRNA delivery. We previously reported that treatment of airway epithelia with specific small molecules improves oligonucleotide uptake and facilitates RNAi responses. Here, we exploited the platelet activating facto...

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Main Authors: Krishnamurthy, Sateesh, Behlke, Mark A, Apicella, Michael A, McCray, Paul B, Davidson, Beverly L
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121516/
https://ncbi.nlm.nih.gov/pubmed/25025465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.26
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