Gene promoter methylation in colorectal cancer and healthy adjacent mucosa specimens: Correlation with physiological and pathological characteristics, and with biomarkers of one-carbon metabolism

We evaluated the promoter methylation levels of the APC, MGMT, hMLH1, RASSF1A and CDKN2A genes in 107 colorectal cancer (CRC) samples and 80 healthy adjacent tissues. We searched for correlation with both physical and pathological features, polymorphisms of folate metabolism pathway genes (MTHFR, MT...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Coppedè, Fabio, Migheli, Francesca, Lopomo, Angela, Failli, Alessandra, Legitimo, Annalisa, Consolini, Rita, Fontanini, Gabriella, Sensi, Elisa, Servadio, Adele, Seccia, Massimo, Zocco, Giuseppe, Chiarugi, Massimo, Spisni, Roberto, Migliore, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121372/
https://ncbi.nlm.nih.gov/pubmed/24500500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.27956
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados