Comparison Study of MS-HRM and Pyrosequencing Techniques for Quantification of APC and CDKN2A Gene Methylation

There is increasing interest in the development of cost-effective techniques for the quantification of DNA methylation biomarkers. We analyzed 90 samples of surgically resected colorectal cancer tissues for APC and CDKN2A promoter methylation using methylation sensitive-high resolution melting (MS-H...

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Main Authors: Migheli, Francesca, Stoccoro, Andrea, Coppedè, Fabio, Wan Omar, Wan Adnan, Failli, Alessandra, Consolini, Rita, Seccia, Massimo, Spisni, Roberto, Miccoli, Paolo, Mathers, John C., Migliore, Lucia
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543439/
https://ncbi.nlm.nih.gov/pubmed/23326336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052501
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