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Synergistic chromatin repression of the tumor suppressor gene RARB in human prostate cancers
DNA methylation and polycomb proteins are well-known mediators of epigenetic silencing in mammalian cells. Usually described as mutually exclusive, this statement is today controversial and recent in vitro studies suggest the co-existence of both repressor systems. We addressed this issue in the stu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121358/ https://ncbi.nlm.nih.gov/pubmed/24492483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.27869 |
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