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A potential therapeutic effect of CYP2C8 overexpression on anti-TNF-α activity

Epoxyeicosatrienoic acids (EETs) are generated from arachidonic acid catalysed by cytochrome P450 (CYP) epoxygenases. In addition to regulating vascular tone EETs may alleviate inflammation and ROS. The present study was conducted to determine whether CYP2C8 gene overexpression was able to increase...

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Bibliographic Details
Main Authors: LIU, WANJUN, WANG, BEI, DING, HU, WANG, DAO WEN, ZENG, HESONG
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121355/
https://ncbi.nlm.nih.gov/pubmed/25017038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2014.1844
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