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A potential therapeutic effect of CYP2C8 overexpression on anti-TNF-α activity

Epoxyeicosatrienoic acids (EETs) are generated from arachidonic acid catalysed by cytochrome P450 (CYP) epoxygenases. In addition to regulating vascular tone EETs may alleviate inflammation and ROS. The present study was conducted to determine whether CYP2C8 gene overexpression was able to increase...

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Detalhes bibliográficos
Main Authors: LIU, WANJUN, WANG, BEI, DING, HU, WANG, DAO WEN, ZENG, HESONG
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121355/
https://ncbi.nlm.nih.gov/pubmed/25017038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2014.1844
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