Andrographolide Inhibits Nuclear Factor-κB Activation through JNK-Akt-p65 Signaling Cascade in Tumor Necrosis Factor-α-Stimulated Vascular Smooth Muscle Cells

Critical vascular inflammation leads to vascular dysfunction and cardiovascular diseases, including abdominal aortic aneurysms, hypertension, and atherosclerosis. Andrographolide is the most active and critical constituent isolated from the leaves of Andrographis paniculata, a herbal medicine widely...

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Autors principals: Chen, Yu-Ying, Hsu, Ming-Jen, Hsieh, Cheng-Ying, Lee, Lin-Wen, Chen, Zhih-Cherng, Sheu, Joen-Rong
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121194/
https://ncbi.nlm.nih.gov/pubmed/25114952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/130381
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