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Andrographolide Inhibits Nuclear Factor-κB Activation through JNK-Akt-p65 Signaling Cascade in Tumor Necrosis Factor-α-Stimulated Vascular Smooth Muscle Cells

Critical vascular inflammation leads to vascular dysfunction and cardiovascular diseases, including abdominal aortic aneurysms, hypertension, and atherosclerosis. Andrographolide is the most active and critical constituent isolated from the leaves of Andrographis paniculata, a herbal medicine widely...

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Dettagli Bibliografici
Autori principali: Chen, Yu-Ying, Hsu, Ming-Jen, Hsieh, Cheng-Ying, Lee, Lin-Wen, Chen, Zhih-Cherng, Sheu, Joen-Rong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121194/
https://ncbi.nlm.nih.gov/pubmed/25114952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/130381
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