Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.

Multidrug-resistance-associated protein (MRP) is a plasma membrane glycoprotein that can confer multidrug resistance (MDR) by lowering intracellular drug concentration. Here we demonstrate that depletion of intracellular glutathione by DL-buthionine (S,R)-sulfoximine results in a complete reversal o...

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Detalhes bibliográficos
Main Authors: Zaman, G J, Lankelma, J, van Tellingen, O, Beijnen, J, Dekker, H, Paulusma, C, Oude Elferink, R P, Baas, F, Borst, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC41211/
https://ncbi.nlm.nih.gov/pubmed/7644478
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