IGF1R Signaling Is Necessary for FSH-Induced Activation of AKT and Differentiation of Human Cumulus Granulosa Cells

CONTEXT: FSH is routinely administered to in vitro fertilization patients to induce follicle maturation. During this process, granulosa cells differentiate and acquire specific functional characteristics that are required to coordinate ovulation and oocyte maturation. OBJECTIVE: The objective of the...

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Hlavní autoři: Baumgarten, Sarah C., Convissar, Scott M., Fierro, Michelle A., Winston, Nicola J., Scoccia, Bert, Stocco, Carlos
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2014
Témata:
Endocrine Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121023/
https://ncbi.nlm.nih.gov/pubmed/24848710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-1139
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