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IGF1R Signaling Is Necessary for FSH-Induced Activation of AKT and Differentiation of Human Cumulus Granulosa Cells

CONTEXT: FSH is routinely administered to in vitro fertilization patients to induce follicle maturation. During this process, granulosa cells differentiate and acquire specific functional characteristics that are required to coordinate ovulation and oocyte maturation. OBJECTIVE: The objective of the...

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Bibliografski detalji
Glavni autori: Baumgarten, Sarah C., Convissar, Scott M., Fierro, Michelle A., Winston, Nicola J., Scoccia, Bert, Stocco, Carlos
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121023/
https://ncbi.nlm.nih.gov/pubmed/24848710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-1139
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