IGF1R Signaling Is Necessary for FSH-Induced Activation of AKT and Differentiation of Human Cumulus Granulosa Cells

CONTEXT: FSH is routinely administered to in vitro fertilization patients to induce follicle maturation. During this process, granulosa cells differentiate and acquire specific functional characteristics that are required to coordinate ovulation and oocyte maturation. OBJECTIVE: The objective of the...

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Bibliographic Details
Main Authors: Baumgarten, Sarah C., Convissar, Scott M., Fierro, Michelle A., Winston, Nicola J., Scoccia, Bert, Stocco, Carlos
Format: Artigo
Language:Inglês
Published: Endocrine Society 2014
Subjects:
Endocrine Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121023/
https://ncbi.nlm.nih.gov/pubmed/24848710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-1139
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