IGF1R Signaling Is Necessary for FSH-Induced Activation of AKT and Differentiation of Human Cumulus Granulosa Cells

CONTEXT: FSH is routinely administered to in vitro fertilization patients to induce follicle maturation. During this process, granulosa cells differentiate and acquire specific functional characteristics that are required to coordinate ovulation and oocyte maturation. OBJECTIVE: The objective of the...

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Detalhes bibliográficos
Main Authors: Baumgarten, Sarah C., Convissar, Scott M., Fierro, Michelle A., Winston, Nicola J., Scoccia, Bert, Stocco, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
Endocrine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121023/
https://ncbi.nlm.nih.gov/pubmed/24848710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-1139
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