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Role of Caspase-3 Cleaved IP(3)R1 on Ca(2+) Homeostasis and Developmental Competence of Mouse Oocytes and Eggs
Apoptosis in most cell types is accompanied by altered Ca(2+) homeostasis. During apoptosis, caspase-3 mediated cleavage of the type 1 inositol 1,4,5-trisphosphate receptor (IP(3)R1) generates a 95-kDa C-terminal fragment (C-IP(3)R1), which represents the channel domain of the receptor. Aged mouse e...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4120966/ https://ncbi.nlm.nih.gov/pubmed/24692207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24638 |
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