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Protection by inosine in a cellular model of Parkinson’s disease

Inosine (hypoxanthine 9-beta-D-ribofuranoside), a purine nucleoside with multiple intracellular roles, also serves as an extracellular modulatory signal. On neurons, it can produce anti-inflammatory and trophic effects that confer protection against toxic influences in vivo and in vitro. The protect...

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Main Authors: Cipriani, Sara, Bakshi, Rachit, Schwarzschild, Michael A.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120965/
https://ncbi.nlm.nih.gov/pubmed/24880154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.05.038
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