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Autism-Associated Neuroligin-3 Mutations Commonly Impair Striatal Circuits to Boost Repetitive Behaviors

In humans, neuroligin-3 mutations are associated with autism, while in mice the corresponding mutations produce robust synaptic and behavioral changes. However, different neuroligin-3 mutations cause largely distinct phenotypes in mice, and no causal relationship links a specific synaptic dysfunctio...

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Autors principals: Fuccillo, Marc V., Rothwell, Patrick E., Maxeiner, Stephan, Hayton, Scott J., Gokce, Ozgun, Lim, Byung Kook, Fowler, Stephen C., Malenka, Robert C., Südhof, Thomas C.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120877/
https://ncbi.nlm.nih.gov/pubmed/24995986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.04.045
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