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LOSS OF MELANOCORTIN-4 RECEPTOR FUNCTION ATTENUATES HPA RESPONSES TO PSYCHOLOGICAL STRESS

The melanocortin 4 receptor (MC4R), well-known for its role in the regulation of energy balance, is widely expressed in stress-regulatory brain regions, including the paraventricular nucleus of the hypothalamus (PVH) and the medial amygdala (MeA). In agreement with this, MC4R has been implicated in...

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Detalhes bibliográficos
Main Authors: Ryan, Karen K., Mul, Joram D., Clemmensen, Christoffer, Egan, Ann E., Begg, Denovan P., Halcomb, Kristen, Seeley, Randy J., Herman, James P., Ulrich-Lai, Yvonne M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120841/
https://ncbi.nlm.nih.gov/pubmed/24636506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2014.01.010
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