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Gender Modifies the Effect of Ursodeoxycholic Acid (UDCA) in a Randomized Controlled Trial in Colorectal Adenoma Patients

BACKGROUND: Ursodeoxycholic acid (UDCA) was one of the earliest agents investigated as a drug for colorectal cancer prevention. However, UDCA failed to demonstrate efficacy to prevent the development of colorectal adenomas in a large phase III randomized controlled trial. We re-evaluated the effect...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Thompson, Patricia A., Wertheim, Betsy C., Roe, Denise J., Ashbeck, Erin L., Jacobs, Elizabeth T., Lance, Peter, Martínez, María Elena, Alberts, David S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120755/
https://ncbi.nlm.nih.gov/pubmed/19952360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-09-0234
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