Endothelial 6-phosphofructo-2-kinase (PFKFB3) plays a critical role in angiogenesis

OBJECTIVE: Vascular cells, particularly endothelial cells, adopt aerobic glycolysis to generate energy to support cellular functions. The effect of endothelial glycolysis on angiogenesis remains unclear. 6-Phosphofructo-2-kinase/fructose-2, 6-bisphosphatase, isoform 3 (PFKFB3), is a critical enzyme...

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Detalhes bibliográficos
Main Authors: Xu, Yiming, An, Xiaofei, Guo, Xin, Habtetsion, Tsadik Ghebreamlak, Wang, Yong, Xu, Xizhen, Kandala, Sridhar, Li, Qinkai, Li, Honggui, Zhang, Chunxiang, Caldwell, Ruth B., Fulton, David J., Su, Yunchao, Hoda, Md Nasrul, Zhou, Gang, Wu, Chaodong, Huo, Yuqing
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120754/
https://ncbi.nlm.nih.gov/pubmed/24700124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.303041
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