Next-generation sequencing reveals large connected networks of intra-host HCV variants

BACKGROUND: Next-generation sequencing (NGS) allows for sampling numerous viral variants from infected patients. This provides a novel opportunity to represent and study the mutational landscape of Hepatitis C Virus (HCV) within a single host. RESULTS: Intra-host variants of the HCV E1/E2 region wer...

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Autors principals: Campo, David S, Dimitrova, Zoya, Yamasaki, Lilian, Skums, Pavel, Lau, Daryl TY, Vaughan, Gilberto, Forbi, Joseph C, Teo, Chong-Gee, Khudyakov, Yury
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120142/
https://ncbi.nlm.nih.gov/pubmed/25081811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-S5-S4
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