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A pilot study of preoperative gefitinib for early stage lung cancer to assess intratumor drug concentration and pathways mediating primary resistance
BACKGROUND: Targeted agents such as tyrosine kinase inhibitors have been extensively studied in pre-clinical systems as well as in advanced stage patients. Little is known about levels of kinase inhibitors found in tumors as opposed to plasma. Similarly, effects of inhibitors on tumor signaling path...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4120062/ https://ncbi.nlm.nih.gov/pubmed/20881637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e3181f38f70 |
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