Accumulation of small hyaluronan oligosaccharides in tumour interstitial fluid correlates with lymphatic invasion and lymph node metastasis

BACKGROUND: Association studies have implicated the glycosaminoglycan hyaluronan (hyaluronic acid, HA) and its degrading enzymes the hyaluronidases in tumour progression and metastasis. Oligosaccharides of degraded HA have been ascribed a number of biological functions that are not exerted by high-m...

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Main Authors: Schmaus, A, Klusmeier, S, Rothley, M, Dimmler, A, Sipos, B, Faller, G, Thiele, W, Allgayer, H, Hohenberger, P, Post, S, Sleeman, J P
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Molecular Diagnostics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119989/
https://ncbi.nlm.nih.gov/pubmed/24937668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.332
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