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Overcoming transport barriers for interstitial-, lymphatic-, and lymph node-targeted drug delivery
Despite drug formulation improving circulation times and targeting, efficacy is stymied by inadequate penetration into and retention within target tissues. This review highlights the barriers restricting delivery to the connective tissue interstitium, lymphatics, and lymph nodes as well as advances...
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| Publicado no: | Curr Opin Chem Eng |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4345645/ https://ncbi.nlm.nih.gov/pubmed/25745594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coche.2014.11.003 |
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