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Overcoming transport barriers for interstitial-, lymphatic-, and lymph node-targeted drug delivery
Despite drug formulation improving circulation times and targeting, efficacy is stymied by inadequate penetration into and retention within target tissues. This review highlights the barriers restricting delivery to the connective tissue interstitium, lymphatics, and lymph nodes as well as advances...
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| 發表在: | Curr Opin Chem Eng |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4345645/ https://ncbi.nlm.nih.gov/pubmed/25745594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coche.2014.11.003 |
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