Elevated expression of myosin X in tumours contributes to breast cancer aggressiveness and metastasis

BACKGROUND: Myosin X (MYO10) was recently reported to promote tumour invasion by transporting integrins to filopodial tips in breast cancer. However, the role of MYO10 in tumours remains poorly defined. Here, we report that MYO10 is required in invadopodia to mediate invasive growth and extracellula...

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Bibliographische Detailangaben
Hauptverfasser: Cao, R, Chen, J, Zhang, X, Zhai, Y, Qing, X, Xing, W, Zhang, L, Malik, Y S, Yu, H, Zhu, X
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Molecular Diagnostics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119973/
https://ncbi.nlm.nih.gov/pubmed/24921915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.298
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