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Methylated Eyes Absent 4 (EYA4) Gene Promotor in Non-neoplastic Mucosa of Ulcerative Colitis Patients with Colorectal Cancer: Evidence for a Field Effect

BACKGROUND: Aberrant methylation of the EYA4 gene (mEYA4) highly discriminates ulcerative colitis (UC) cases with colorectal neoplasia from UC controls in both tissue and stool. It is not known if mEYA4 is also present in nonadjacent non-neoplastic mucosa (NNM) of UC patients with colorectal neoplas...

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Detalhes bibliográficos
Main Authors: Kisiel, John B., Garrity-Park, Megan M., Taylor, William R., Smyrk, Thomas C., Ahlquist, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119944/
https://ncbi.nlm.nih.gov/pubmed/23867875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e31829b3f4d
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